Hyalink™ X is a patented technology for preparing cross-linked Hyaluronan hydrogels. The process results in safe and efficacious products with characteristics specified by the client. The Hyalink™X hydrogels are appropriate for all types of clinical, pre-clinical and research/diagnostic applications. Hydrogel properties are specified by the client after consulting with our formulation scientists.  

Hyalink™ X is versatile and adaptable to customers’ specific requirements to produce ready to use devices for many applications and sustained release/depots for drug formulations. 

Benefits of Hyalink™ X  

• Versatile and proven technology producing hydrogels with customized viscoelastic properties,
• Proven scalability for clinical products,
• Well tolerated, safe, biocompatible - 2 decades of use with millions of patient injections

Application Areas

• Dermal fillers and viscous supplements-Highly tunable process to develop new proprietary formulations or to mimic existing commercial products
• Topical formulations-Formulations for topical skincare or wound care applications
• Ophthalmic surgery-OVD (ophthalmic visco-elastic devices) formulations to compliment high molecular weight HA products
• Anti-adhesion-Products for surgical applications to prevent adhesion or to stop post surgery bleedings
• Drug delivery / controlled release-Injectable drug loaded depots to extend release of almost any API, including small molecules, peptides and proteins (see publications),
• Simple biodegradable vehicle and not a New Chemical Entity (NCE) as defined by regulatory authorities

Streamlined business model  for faster time to market

Access to the Hyalink™ X technology (tech transfer + final hydrogel formulation support) is by license or as bulk (non-sterile or sterile) raw material. In either case, Hyamedix can support you in your product development with our extensive knowledge of Hyluronan in order to enable fast product development.

Our R&D capabilities include, but are not limited to, the investigation of hydrogel swelling, rheology, biodegradation, subsequent processing to suit given applications, compatibility with excipients, active pharmaceutical ingredients (APIs), and preservatives. With an established expertise in Hyaluronan and cross linked Hyaluronan, Hyamedix is here to support in the development of your innovative solutions. hyaluronic acid Hyaluronan cross-linking technology hyaluronic acid formulation

With dedicated formulation labs, Hyamedix can develop proprietary custom formulations based on hyaluronan for many application areas including cosmetics, medical devices and pharmaceuticals.

We have extensive experience working with medical device and pharmaceutical clients developing viscous formulations in the areas of dermo-cosmetics (topical and injectable), dermal fillers, mesotherapy, wound care, ophthalmology, orthopaedics and oncology.

We can also support in the area of drug delivery and controlled release.

Hyamedix can support and help with existing client formulations by optimising those formulations for better processability, sterilisation and/or efficacy in the determined application area.

We can support in the following areas:

• Chemical characteristics
• Swelling properties
• Viscoelastic properties
• Injectability
• Heat stability
• General Formulation properties
• Bio stability